The SN2 reaction is favored by polar aprotic solvents – these are solvents such as acetone, DMSO, acetonitrile, or DMF that are polar enough to dissolve the substrate and nucleophile but do not participate in hydrogen bonding with the nucleophile. These also tend to be the nucleophiles for these reactions as well.
Is acetone a polar aprotic solvent?
However, acetone is still considered a polar aprotic solvent, despite the fact that it is relatively acidic, and not significantly less acidic than alcohols. Then again, acetone (and other carbonyl containing solvents) are, indeed, poor solvents when using strong bases due to their relatively high acidity.
What is an example of a polar solvent?
Examples of polar protic solvents: water (H-OH), acetic acid (CH3CO-OH)methanol (CH3-OH), ethanol (CH3CH2-OH), n-propanol (CH3CH2CH2-OH), n-butanol (CH3CH2CH2CH2-OH). ? Dipolar aprotic solvents Dipolar aprotic molecules possess a large bond dipole moment (a measure of polarity of a molecule chemical bond).