21st November 2019

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Which statins are less likely to cause muscle pain?

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In this regard, it is interesting to note that in the PRIMO study, the most hydrophilic statins (pravastatin and fluvastatin) were least likely to cause myalgia, whereas simvastatin, the most lipophilic one, was most likely to be associated with muscular adverse effects (4).

Similarly one may ask, which is the statin with the least side effects?

In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general.

What is the safest statin on the market?

Dr. Brinton: Fluvastatin and pravastatin each appears to have fewer drug-drug interactions than other statins. Although some clinicians have felt that the safety of pravastatin was primarily due to its water solubility, the other water-soluble statin, rosuvastatin, has yet to be fully proven as safe.

1

What is the best vitamin for leg cramps?

Additionally, certain vitamins and minerals impact muscle function, particularly potassium and magnesium. A significant body of research has found that increasing your magnesium intake can help with the frequency of night time leg cramps, especially for pregnant women.

2

Are there any cholesterol drugs that are not statins?

Aside from Zetia there haven't been any good non-statin options for lowering LDL Cholesterol. Statin drugs like Lipitor (atorvastatin), Zocor (simvastatin) and Crestor work well to lower the “bad” cholesterol, the LDL, and have remained first line therapy for many years.

3

What cholesterol drugs do not cause muscle pain?

Some examples of statin medications are Lipitor® (atorvastatin), Pravachol® (pravastatin), Zocor® (simvastatin), Livalo® (pitavastatin) and Crestor® (rosuvastatin). Unfortunately, some people may experience muscle pain or weakness while taking statins.

4

Why do statins cause leg pain?

Muscle breakdown. Rhabdomyolysis, or the breakdown of muscle tissue, is a rare side effect of statins that can also cause muscle pain. This disease can cause life-threatening muscle damage. In addition to severe muscle pain, rhabdomyolysis can lead to liver damage, kidney failure, and, in rare cases, death.

5

What are the bad side effects of statin drugs?

The most common statin side effects include:

Headache.
Difficulty sleeping.
Flushing of the skin.
Muscle aches, tenderness, or weakness (myalgia)
Drowsiness.
Dizziness.
Nausea or vomiting.
Abdominal cramping or pain.

6

How can I lower my cholesterol naturally?

6 Dietary and Lifestyle Tips To Lower LDL Levels

Limit your intake of foods full of saturated fats, trans fats, and dietary cholesterol.
Eat a lot more fiber-rich foods (especially soluble fiber from foods like beans, oats, barley, fruits, and vegetables).

7

Do statins make you put on weight?

Statins increase weight and blood sugar levels and raise the risk of diabetes, a study has found, but experts maintain that the benefits of the drug "greatly outweigh" the risks. Now a study has produced strong evidence that the drugs' basic mechanism can lead to weight gain and a modest increase in diabetes risk.

8

What is the most popular statin drug?

Statins that are approved for use in the U.S. include:

atorvastatin (Lipitor),
fluvastatin (Lescol, Lescol XL),
lovastatin (Mevacor, Altoprev),
pravastatin (Pravachol),
rosuvastatin (Crestor),
simvastatin (Zocor), and.
pitavastatin (Livalo).

9

What does muscle pain from statins feel like?

One of the most common complaints of people taking statins is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.

10

What is the least potent statin?

Cerivastatin is the most potent, (withdrawn from the market in August, 2001 due to risk of serious rhabdomyolysis) followed by (in order of decreasing potency), rosuvastatin, atorvastatin, simvastatin, lovastatin, pravastatin, and fluvastatin. The relative potency of pitavastatin has not yet been fully established.

11

Can you drink alcohol while taking a statin?

Medical experts advise not drinking any alcohol while taking statins. If you do drink, though, then it needs to be kept at a moderate level. The primary reason for this would be because drinking a large volume of alcohol while taking statins can drastically increase the risk of side effects.

12

What are the bad side effects of Crestor?

Less serious side effects may include:

headache, depressed mood;
mild muscle pain;
joint pain;
sleep problems (insomnia), nightmares;
constipation;
mild nausea; or.
stomach pain or indigestion.

13

Is neuropathy from statins reversible?

26% of individuals over 65 years of age (without a predisposing disease known to cause neuropathy) will develop peripheral neuropathy at some point in life. There are reported cases of statin induced peripheral neuropathy, which in the initial stages can be reversible.

14

Which statin has lowest risk of myopathy?

Very approximately, (because there are so many interacting factors), the likelihood of being associated with a myopathy, from least likely to most likely among the currently available statins are: pravastatin, fluvastatin, rosuvastatin, atorvastatin, lovastatin and simvastatin.

15

Is Lipitor a statin?

Statins—a class of drug that includes atorvastatin (Lipitor), simvastatin (Zocor), and others—are among the most effective drugs for lowering cholesterol. They are also among the most widely prescribed drugs of all time.

16

What are the symptoms of statin myopathy?

Myopathy is separated into three different types based on toxicity:

Myalgia refers to generalized pain in the muscles.
Myositis presents itself with muscle pain, tenderness, or weakness and a higher level of creatine kinase in the bloodstream.
Rhabdomyolysis is an extreme, life-threatening type of myopathy.

17

Which statin has the least amount of side effects?

In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general.

18

What are the side effects of atorvastatin?

Stop taking atorvastatin and call your doctor at once if you have any of these serious side effects:

unexplained muscle pain, tenderness, or weakness;
confusion, memory problems;
fever, unusual tiredness, and dark colored urine;
swelling, weight gain, urinating less than usual or not at all;

19

Which cholesterol drug is safest?

The Most Common Cholesterol Meds: Statins

Atorvastatin (Lipitor)
Fluvastatin (Lescol)
Lovastatin.
Pitavastatin (Livalo)
Pravastatin (Pravachol)
Rosuvastatin calcium (Crestor)
Simvastatin (Zocor)

20

How long does it take for atorvastatin to get out of your system?

So it would take about 77 hours for atorvastatin to be out of your system.

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