2nd October 2019

nih
13

Which is the female chromosome?

Each person normally has one pair of sex chromosomes in each cell. Females have two X chromosomes, while males have one X and one Y chromosome. Early in embryonic development in females, one of the two X chromosomes is randomly and permanently inactivated in cells other than egg cells.

Also question is, how does a girl become a carrier?

A baby girl will inherit an X chromosome with a dominant gene for normal blood clotting from her father. If she gets the X chromosome with the hemophilia gene she will be a carrier. So a carrier's daughter has a 50% chance of being a carrier.

What is a Barr body and where is it found?

The inactivated X chromosome physically condenses to form a Barr body. And we can see them as a small structure found at the rim of the nucleus in female somatic cells between divisions.

Can a woman with hemophilia have a baby?

A female who inherits one affected X chromosome becomes a “carrier” of hemophilia. She can pass the affected gene on to her children. In addition, a female who is a carrier sometimes can have symptoms of hemophilia. In fact, some doctors describe these women as having mild hemophilia.
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