The Grignard reaction (pronounced /gri?ar/) is an organometallic chemical reaction in which alkyl, vinyl, or aryl-magnesium halides (Grignard reagents) add to a carbonyl group in an aldehyde or ketone. This reaction is an important tool for the formation of carbon–carbon bonds.
Correspondingly, do Grignard reagents react with alcohols?
They're also very strong bases and will react with acidic hydrogens (such as alcohols, water, and carboxylic acids). Similar to or the same as: very similar to organolithium reagents. Examples: Grignard reagents are made through the addition of magnesium metal to alkyl or alkenyl halides.
What type of solvents can be used in Grignard reactions?
q Diethyl ether is an especially good solvent for the formation of Grignard reagents because ethers are non-acidic (aprotic). Water or alcohols would protonate and thus destroy the Grignard reagent, because the Grignard carbon is highly nucleophilic. This would form a hydrocarbon.