What kind of pain reliever can I take with Xarelto?
These over-the-counter painkillers -- called nonsteroidal anti-inflammatory drugs (NSAIDs) -- include such drugs as Advil, Aleve, Bufferin, Excedrin, Motrin and Nuprin, as well as aspirin. Patients who use blood thinners such as warfarin, Eliquis, Xarelto or Pradaxa should not take them, the researchers said.
"The message for people is if you're taking a blood thinner, do not take an NSAID -- just don't take one," Davidson said. "If you have a headache or aching muscles or joints, take generic Tylenol [acetaminophen]. Don't take NSAIDs for casual use," he added.
- Ibuprofen, which is found in Motrin and Advil, belongs to a widely used class of pain relievers known as nonsteroidal anti-inflammatory drugs. In the study, when a single dose of ibuprofen was taken beforehand, aspirin lost 98 percent of its blood-thinning power.
- Liver damage. Acetaminophen, the leading nonprescription pain reliever, does not cause GI bleeding, but long-term frequent use or even large single doses can cause severe liver damage.
- You should not take this medicine if you are allergic to aspirin or oxycodone (OxyContin), or if you have: a bleeding or blood clotting disorder such as hemophilia; ulcer or obstruction in the stomach; if you are taking a blood thinner such as warfarin (Coumadin, Jantoven).
No, you cannot take ibuprofen while taking Xarelto. People who take Xarelto must be careful avoid over-the-counter pain relievers because they can cause you to bleed. Ibuprofen (Advil, Motrin) Naproxen (Aleve)
- Adverse Medication Interactions Involving Xarelto
- Other blood thinners like warfarin (Coumadin), clopidogrel (Plavix), etc.
- Medications used to treat blood and circulation problems like cilostazol (Pletal), etc.
- Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil), naproxen (Aleve), aspirin, etc.
- Types of drugs that interact with Xarelto include:
- Other blood thinners.
- Drugs used to treat blood or circulation problems.
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Certain heart medications.
- Anti-seizure drugs, such as carbamazepine (Tegretol)
- Antifungal medications.
- Drugs used to treat HIV.
- XARELTO® also has fewer drug-drug interactions than warfarin. But like all blood thinners, you have a higher risk of bleeding if you take XARELTO® with other medicines, like aspirin, NSAIDs, warfarin, heparin or clopidogrel, that increase your risk of bleeding.
Updated: 16th October 2019