2nd October 2019


What is the role of calcium in muscle contraction and relaxation?

With each contraction cycle, actin moves relative to myosin. The muscle contraction cycle is triggered by calcium ions binding to the protein complex troponin, exposing the active-binding sites on the actin.

Likewise, what does calcium do in muscles?

When the brain signals the muscle to contract, the body pulls calcium from the blood into the muscle cells. The calcium binds with the troponin and draws it out of position. When the troponin and tropomyosin move, this activates the actin and myosin to move toward each other and contract the muscle.

How is calcium used in muscle contraction?

Vertebrate striated muscle contraction is controlled (regulated) by the action of the proteins troponin and tropomyosin on the actin filaments. Nervous stimulation causes a depolarisation of the muscle membrane (sarcolemma) which triggers the release of calcium ions from the sarcoplasmic reticulum.
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