What is the measure of a kilometer?


What does Km and kcat mean?

The second order rate constant kcat/Km indicates the catalytic efficiency. of the enzyme: A direct measure of the efficiency of the enzyme in transforming Subst. kcat/Km combines: the effectiveness of transformation of bound product. the effectiveness of productive substrate binding.
  • What is KD of an enzyme?

    Kd, however, is the dissociation constant, and measures the dissociation of the substrate from the ES complex. Therefore, the larger Kd is, the less affinity the enzyme has for the substrate.
  • What is Ki in biochemistry?

    The Ki is the concentration of inhibitor at which under saturating substrate conditions the reaction rate is half of the maximum reaction rate Vmax. A good inhibitor inhibits in the nanomolar range. Sometimes an inhibition in the lower micromolar range can still be acceptable. A Ki of 31 mM is simply bad.
  • What does positive cooperativity mean?

    One manifestation of this is enzymes or receptors that have multiple binding sites where the affinity of the binding sites for a ligand is apparently increased, positive cooperativity, or decreased, negative cooperativity, upon the binding of a ligand to a binding site.

Updated: 16th October 2019

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