Rough ER is found throughout the cell but the density is higher near the nucleus and the Golgi apparatus. Ribosomes on the rough endoplasmic reticulum are called 'membrane bound' and are responsible for the assembly of many proteins. This process is called translation.
Similarly one may ask, what is the main function of the rough endoplasmic reticulum?
The rough endoplasmic reticulum is a series of connected flattened sacs that have many ribosomes on their outer surface. Rough endoplasmic reticulum synthesizes and secretes serum proteins (such as albumin) in the liver, and hormones (such as insulin) and other substances (such as milk) in the glands.
What are the functions of the SER and RER?
The rough endoplasmic reticulum is especially prominent in cells such as hepatocytes. The smooth endoplasmic reticulum lacks ribosomes and functions in lipid manufacture and metabolism, the production of steroid hormones, and detoxification. The smooth ER is especially abundant in mammalian liver and gonad cells.
What is the function of the rough and smooth endoplasmic reticulum?
The smooth ER also regulates and releases calcium ions and processes toxins. It is described as 'smooth' to distinguish it from rough ER, which has ribosomes for protein synthesis on its surface. Each organelle in the cytoplasm of a cell is responsible for performing a certain function.