What is the function of G cells?

In anatomy, the G cell (or γ-cell) is a type of cell in the stomach and duodenum that secretes gastrin. It works in conjunction with gastric chief cells and parietal cells. G cells are found deep within the pyloric glands of the stomach antrum, and occasionally in the pancreas and duodenum.
A.

What is the function of the parietal cells?

Parietal cells (also known as oxyntic or delomorphous cells), are the epithelial cells that secrete hydrochloric acid (HCl) and intrinsic factor. These cells are located in the gastric glands found in the lining of the fundus and in the cardia of the stomach.
  • Where are chief cells found in the body?

    Gastric chief cells are generally located deep in the mucosal layer of the stomach lining. Chief cells release the zymogen (enzyme precursor) pepsinogen when stimulated by a variety of factors including cholinergic activity from the vagus nerve and acidic condition in the stomach.
  • Are parietal cells endocrine or exocrine?

    The secretions of the exocrine gastric glands - composed of the mucous, parietal, and chief cells - make up the gastric juice. The products of the endocrine cells are secreted directly into the bloodstream and are not a part of the gastric juice.
  • What is pepsin and what does it do?

    Pepsin is an endopeptidase that breaks down proteins into smaller peptides (that is, a protease). It is produced in the stomach and is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food.
B.

What is the function of the chief cell?

Chief cells (B or arrow) are located, in cluster, at the base of the glands. They synthesize and secret hydrolytic enzymes, which are activated at acid pH. These enzymes include gastric lipase, rennin and pepsin, which is secreted as pepsinogen and activated in the lumen. Pepsin hydrolyzes proteins.
  • What is the function of parietal cells?

    Parietal cells (also known as oxyntic or delomorphous cells), are the epithelial cells that secrete hydrochloric acid (HCl) and intrinsic factor. These cells are located in the gastric glands found in the lining of the fundus and in the cardia of the stomach.
  • What is the function of chief cells?

    The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases pepsinogen and chymosin. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with acid produced by gastric parietal cells.
  • What chemicals are released by cells in the stomach?

    Parietal cells (also called oxyntic cells) are the stomach epithelium cells which secrete gastric acid. Parietal cells produce gastric acid (hydrochloric acid) in response to histamine (via H2 receptors), acetylcholine (M3 receptors) and gastrin (gastrin receptors).
C.

What are the secretions of parietal and chief cells?

The two main types of exocrine secretory cells of the stomach are parietal cells and chief cells. Parietal cells secrete hydrochloric acid and chief cells secrete digestive enzymes such as pepsin.
  • What is the function of goblet cells in the small intestine?

    Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins.
  • Do Chief cells secrete hydrochloric acid?

    One important component of gastric juice is pepsin. Pepsin is the chief digestive enzyme in the stomach that breaks down proteins. We see that chief cells produce pepsinogen (an inactive form of pepsin). Pepsinogen is converted to pepsin when the parietal cells found within the gastric glands secrete hydrochloric acid.
  • What is the function of parietal cells?

    Parietal cells (also known as oxyntic or delomorphous cells), are the epithelial cells that secrete hydrochloric acid (HCl) and intrinsic factor. These cells are located in the gastric glands found in the lining of the fundus and in the cardia of the stomach.

Updated: 3rd October 2019

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