28th August 2018

wikipedia
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What is the distribution coefficient?

In the physical sciences, a partition-coefficient (P) or distribution-coefficient (D) is the ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium. In the chemical and pharmaceutical sciences, both phases usually are solvents.

In this manner, what is log P in chemistry?

log P Definitions. According to the International Union of Pure and Applied Chemistry (IUPAC)*: “Lipophilicity represents the affinity of a molecule or a moiety for a lipophilic environment. It is commonly measured by its distribution in a biphasic system (e.g. partition coefficient in octanol-water)”.

How is partition coefficient measured?

In the physical sciences, a partition-coefficient (P) or distribution-coefficient (D) is the ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium. Hence the partition coefficient measures how hydrophilic ("water-loving") or hydrophobic ("water-fearing") a chemical substance is.
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