What is prescribed for pain if you take blood thinners?

Blood thinners are usually given to people at risk for developing blood clots from conditions such as abnormal heart rhythms. Use of these lifesaving medications requires caution with other drugs, especially painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil) or naproxen (Aleve).
A.

Is it OK to take ibuprofen with Xarelto?

No, you cannot take ibuprofen while taking Xarelto. People who take Xarelto must be careful avoid over-the-counter pain relievers because they can cause you to bleed. Ibuprofen (Advil, Motrin)
  • What are the drug interactions with Xarelto?

    Types of drugs that interact with Xarelto include:
    • Other blood thinners.
    • Drugs used to treat blood or circulation problems.
    • Non-steroidal anti-inflammatory drugs (NSAIDs)
    • Certain heart medications.
    • Anti-seizure drugs, such as carbamazepine (Tegretol)
    • Antibiotics.
    • Antifungal medications.
    • Drugs used to treat HIV.
  • Can you take Aleve while on Xarelto?

    These over-the-counter painkillers -- called nonsteroidal anti-inflammatory drugs (NSAIDs) -- include such drugs as Advil, Aleve, Bufferin, Excedrin, Motrin and Nuprin, as well as aspirin. Patients who use blood thinners such as warfarin, Eliquis, Xarelto or Pradaxa should not take them, the researchers said.
  • Can you take paracetamol and rivaroxaban?

    You can take paracetamol while you're taking rivaroxaban. Do not take aspirin and ibuprofen while you're taking rivaroxaban unless a doctor has said it's OK to. They increase the chance of bleeding.
B.

What medications should not be taken with Xarelto?

Adverse Medication Interactions Involving Xarelto
  • Other blood thinners like warfarin (Coumadin), clopidogrel (Plavix), etc.
  • Medications used to treat blood and circulation problems like cilostazol (Pletal), etc.
  • Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil), naproxen (Aleve), aspirin, etc.
  • Can you drink alcohol while on Xarelto?

    This medication may cause stomach bleeding. Daily use of alcohol while using this medicine will increase your risk for stomach bleeding. Limit alcoholic beverages. Ask your doctor or pharmacist about how much alcohol you may safely drink.
  • What is prescribed for pain if you take blood thinners?

    Blood thinners are usually given to people at risk for developing blood clots from conditions such as abnormal heart rhythms. Use of these lifesaving medications requires caution with other drugs, especially painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil) or naproxen (Aleve).
  • What drugs should not be taken with Xarelto?

    Xarelto may also interact with NSAIDs such as:
    • Aspirin.
    • Ibuprofen (Advil, Motrin and other brands)
    • Indomethacin (Indocin)
    • Naproxen (Aleve, Anaprox, Naprelan and other brands)

Updated: 16th October 2019

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