What is immune globulin used to treat?
Gammagard Liquid [Immune Globulin Intravenous (Human)] 10% is a preparation of highly purified and concentrated immunoglobulin G (IgG) antibodies used to treat primary immune deficiency, and to reduce the risk of infection in individuals with poorly functioning immune systems such as those with chronic lymphocytic
An immunoglobulin test measures the level of certain immunoglobulins, or antibodies, in the blood. Antibodies are proteins made by the immune system to fight antigens, such as bacteria, viruses, and toxins. The body makes different immunoglobulins to combat different antigens.
- Immunoglobulin A (IgA), as the principal antibody class in the secretions that bathe these mucosal surfaces, acts as an important first line of defence. IgA, also an important serum immunoglobulin, mediates a variety of protective functions through interaction with specific receptors and immune mediators.
- Positive IgM and IgG tests for dengue antibodies detected in an initial blood sample mean that it is likely that the person became infected with dengue virus within recent weeks. IgM antibody tests can be positive if a person has been infected with a similar virus, such as chikungunya (called cross-reaction).
- While IgM is an indicator of a current infection, an IgG indicates a recent or past exposure to the illness. IgM is the first antibody that the body produces in an acute infection. It is approximately six times larger than IgG and is multivalent. This means that it has multiple binding sites.
Your body's immune system normally makes enough antibodies to fight germs that cause infections. IVIg gives you antibodies that your body is not making on its own so you can fight infections. In autoimmune diseases like lupus, the treatment may help your body raise low red-blood-cell counts.
- Infusion of IVIG preparations may cause osmotic-induced acute renal failure. Despite the fact that this entity has been reported previously, it is not a widely appreciated complication. However, underlying renal insufficiency increases the risk of renal failure.
- Intravenous immunoglobulin (IVIG) is a blood product prepared from the serum of between 1000 and 15 000 donors per batch. It is the treatment of choice for patients with antibody deficiencies.
- Intravenous immunoglobulin: A sterile solution of concentrated antibodies extracted from healthy people that is administered directly into a vein. Abbreviated IVIG. IVIG is used to treat disorders of the immune system or to boost the immune response to serious illness. Also known as intravenous gamma globulin (IGG).
How does Intravenous Immunoglobulin Therapy (IVIg) work? Your body's immune system normally makes enough antibodies to fight germs that cause infections, but if you have an immune deficiency, your body can't make enough of them. IVIg gives you antibodies that your body can't make on its own so you can fight infections.
- Various mild and moderate reactions, such as headache, fever, fatigue, chills, flushing, dizziness, urticaria, wheezing or chest tightness, nausea, vomiting, rigors, back pain, chest pain, muscle cramps, and changes in blood pressure may occur with infusions of Immune Globulin Intravenous (Human).
- SCIg Therapy involves receiving subcutaneous immunoglobulin through a subcutaneous (beneath the skin) infusion. SCIg infusions are given by slowly injecting the immunoglobulin into the fatty tissue (subcutaneous layer) just underneath the skin.
- Hizentra should be administered subcutaneously only. Do not administer intravenously. Hizentra can be dosed daily up to every 2 weeks, using an infusion pump and small needle(s).
Updated: 2nd November 2019