What is BSA in chemotherapy?
In physiology and medicine, the body surface area (BSA) is the measured or calculated surface area of a human body. Nevertheless, there have been several important critiques of the use of BSA in determining the dosage of medications with a narrow therapeutic index, such as chemotherapy.
In physiology and medicine, the body surface area (BSA) is the measured or calculated surface area of a human body. For many clinical purposes BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass.
- The "normal" body surface area is generally taken to be 1.7 m2 but, in actual fact, the body surface area depends on more than just height and weight. Other influential factors include the age and gender of the individual. For example: Average body surface area for adult men: 1.9 m2.
- Body surface area (BSA) is a measurement of the surface of the body using height and weight. There are a few formulas to calculate BSA but there is one formula recommended to use it's called. "The Mostellar Formula" OR BSA (m²) = *wt(Lbs), ht(in)
- Medical Definition of Body mass index. Abbreviated BMI. BMI is a person's weight in kilograms (kg) divided by his or her height in meters squared. The National Institutes of Health (NIH) now defines normal weight, overweight, and obesity according to BMI rather than the traditional height/weight charts.
Body surface area in normal-weight, overweight, and obese adults. Values for body surface area (BSA) are commonly used in medicine, particularly to calculate doses of chemotherapeutic agents and index cardiac output.
- The pulmonary capillary wedge pressure or PCWP (also called the pulmonary wedge pressure or PWP, or pulmonary artery occlusion pressure or PAOP) or cross-sectional pressure, is the pressure measured by wedging a pulmonary catheter with an inflated balloon into a small pulmonary arterial branch.
- It is clinically acceptable to measure the pressure required to fill the ventricles as an indirect assessment of ventricular preload. Left atrial filling pressure or pulmonary artery wedge pressure is used to assess left ventricular preload. Right atrial pressure is used to assess right ventricular preload.
- The simple way to calculate the patients MAP is to use the following formula: MAP = [ (2 x diastolic) + systolic ] divided by 3. The reason that the diastolic value is multiplied by 2, is that the diastolic portion of the cardiac cycle is twice as long as the systolic.
Bovine serum albumin (often from a fetal bovine source) is also used as a nutrient in cell and microbial culture. In molecular biology BSA is used to stabilize some restriction enzymes during digestion of DNA and to prevent adhesion of the enzyme to reaction tubes, pipet tips, and other vessels.
- Bovine serum albumin (also known as BSA or "Fraction V") is a serum albumin protein derived from cows. It is often used as a protein concentration standard in lab experiments.
- Bradford protein assay. It is a quick and accurate spectroscopic analytical procedure used to measure the concentration of protein in a solution. It is subjective, i.e., dependent on the amino acid composition of the measured protein.
- Fetal bovine serum is a by-product of the Dairy Industry. Fetal bovine serum, as with the vast majority of animal serum used in cell culture, is produced from blood collected at commercial slaughterhouses from dairy cattle that also supply meat intended for human consumption.
Updated: 2nd October 2019