Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones, primarily cortisol; but may also include impaired production of aldosterone (a mineralocorticoid), which regulates sodium conservation, potassium secretion, and water retention.
Considering this, what does the HPA axis do?
The hypothalamic pituitary adrenal (HPA) axis is our central stress response system. The HPA axis is an eloquent and every-dynamic intertwining of the central nervous system and endocrine system. This system works in a fairly straight-forward manner.
What is HPA axis dysfunction?
HPA Axis Dysfunction. The HPA axis is a complicated set of relationships and signals that exist between the hypothalamus, the pituitary gland and the adrenals. This relationship is an absolutely indispensable part of our existence.
What is HPA axis activation?
The combined system of CRH-ACTH-cortisol release is referred to as the hypothalamic-pituitary-adrenal axis (or HPA axis). The ultimate result of the HPA axis activation is to increase levels of cortisol in the blood during times of stress.