The first step to screen patients for PSC is to do blood tests. In PSC, liver test should be evaluated. Specifically, the liver blood test called alkaline phosphatase (AP) is often abnormal, though a small percent of patients with PSC may have normal levels.
Considering this, what are the symptoms of primary sclerosing cholangitis?
Signs and symptoms that may appear as the disease progresses include:
- Pain in the upper right part of the abdomen.
- Night sweats.
- Enlarged liver.
- Enlarged spleen.
- Weight loss.
- Yellow eyes and skin (jaundice)
How do you treat primary sclerosing cholangitis?
To prevent and treat these infections, people with primary sclerosing cholangitis may take repeated courses of antibiotics or continue taking antibiotics for long periods. Before any procedure that could cause an infection, such as an endoscopic procedure or abdominal surgery, you'll also need to take antibiotics.
What is the cause of primary sclerosing cholangitis?
The cause of PSC is unknown but it has an association with inflammatory bowel disease, especially ulcerative colitis. It is thought that there may be an autoimmune component to the disease, where the body's immune system attacks the bile ducts in the liver and causes them to become, inflamed and narrowed.