2nd October 2019

sparknotes
15

What enzyme is responsible for the replication of DNA?

DNA Polymerase - The enzyme responsible for catalyzing the addition of nucleotide substrates to DNA both during and after DNA replication. Primase - The enzyme responsible for initiating synthesis of RNA primers on the lagging strand during DNA replication.

Keeping this in view, what enzyme starts DNA replication?

This process makes a template, but replication can't happen because no primer yet exists. See Figure 6 . Chain initiation occurs when a specialized RNA polymerase enzyme called primase makes a short RNA primer. DNA polymerase III extends this RNA primer on both strands.
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