6th October 2019


What does the 5 UTR do?

The 5′ untranslated region (5UTR) (also known as a leader sequence or leader RNA) is the region of an mRNA that is directly upstream from the initiation codon. This region is important for the regulation of translation of a transcript by differing mechanisms in viruses, prokaryotes and eukaryotes.

Also, is there a Shine Dalgarno sequence in eukaryotes?

Shine-Dalgarno sequence in Prokaryotes is the the ribosome landing site. 30S ribosome lands at shine-dalgarno sequence and will scan through the RNA to reach initiator AUG. Initiator AUG may not be immediately after shine-dalgarno sequence. In Eukaryotes, ribosome recruitement is through 5'cap at the end of the mRNA.

What are the binding sites on a ribosome?

A ribosome binding site, or ribosomal binding site (RBS), is a sequence of nucleotides upstream of the start codon of an mRNA transcript that is responsible for the recruitment of a ribosome during the initiation of protein translation.

What is the function of the Kozak sequence?

The Kozak consensus sequence, Kozak consensus or Kozak sequence is a sequence which occurs on eukaryotic mRNA and has the consensus (gcc)gccRccAUGG. The Kozak consensus sequence plays a major role in the initiation of the translation process.
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