2nd October 2019


What does reactive cellular changes mean on a Pap smear?

For many years, InCyte Pathology has reported “reactive cytologic changes” or “ benign cellular changes” for cells in a Pap smear having enlarged, non-dysplastic nuclei. This Pap finding is nonspecific and is usually secondary to an inflammatory or reparative process.

Accordingly, what causes reactive lymphocytes?

Reactive lymphocytes are usually associated with viral illnesses, but they can also be present as a result of drug reactions (such as phenytoin), immunizations, radiation, and hormonal causes (such as stress and Addison's disease), as well as some autoimmune disorders (such as rheumatoid arthritis). Epstein–Barr virus.

What is reactive squamous cells?

Reactive, reparative atypia (presence of immature cells formed in the process of healing or regrowth of the squamous epithelium) is a common finding that often follows treatment of dysplasia and other conditions such as cervical or vaginal infections. It is a benign finding that does not warrant increased surveillance.

What does it mean atypical squamous cells of undetermined significance?

A finding of abnormal cells in the tissue that lines the outer part of the cervix. Atypical squamous cells of undetermined significance is the most common abnormal finding in a Pap test. It may be a sign of infection with certain types of human papillomavirus (HPV). More testing, such as an HPV test, may be needed.
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