Medical Definition of Anion gap. The anion gap can be normal, high, or low. A high anion gap indicated metabolic acidosis, the increased acidity of the blood due to metabolic processes. A low anion gap is relatively rare but may occur from the presence of abnormal positively charged proteins, as in multiple myeloma.
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What happens when PH of blood decreases?
If unchecked, metabolic acidosis leads to acidemia, i.e., blood pH is low (less than 7.35) due to increased production of hydrogen ions by the body or the inability of the body to form bicarbonate (HCO3−) in the kidney. Its causes are diverse, and its consequences can be serious, including coma and death.
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What is AST in a blood test?
The blood test for aspartate aminotransferase (AST) is usually used to detect liver damage. It is often ordered in conjunction with another liver enzyme, alanine aminotransferase (ALT), or as part of a liver panel or comprehensive metabolic panel (CMP) to screen for and/or help diagnose liver disorders.
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What does low AST mean on a blood test?
AST formerly was called serum glutamic oxaloacetic transaminase (SGOT). Low levels of AST are normally found in the blood. When body tissue or an organ such as the heart or liver is diseased or damaged, additional AST is released into the bloodstream. Both ALT and AST levels can test for liver damage.
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What are normal AST and ALT levels?
Normal levels of AST and ALT may slightly vary depending on the individual laboratory's reference values. Typically the range for normal AST is reported between 10 to 40 units per liter and ALT between 7 to 56 units per liter. Mild elevations are generally considered to be 2-3 times higher than the normal range.
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What are the early signs of liver problems?
Signs and Symptoms of Liver Disease. Flu-like symptoms (e.g., fatigue, nausea, vomiting, muscle or joint pain, fever) Loss of appetite. Swelling of abdomen and/or legs.
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What causes ALT and AST to be high?
Elevations of the AST level may also be seen in acute injury to cardiac or skeletal muscle. Common causes of mild increases in AST and ALT levels include non-alcoholic fatty liver disease (NAFLD), hepatitis C, alcoholic fatty liver disease, and medication effect (e.g., due to statins).
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Can you reverse damage to the liver?
Reversing liver damage. The liver is one of the only organs in the body that is able to replace damaged tissue with new cells rather than scar tissue. However, sometimes the liver gets overwhelmed and can't repair itself completely, especially if it's still under attack from a virus, drug, or alcohol.
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What does it mean when you have high AST and ALT levels?
Inflamed or injured liver cells leak higher than normal amounts of certain chemicals, including liver enzymes, into the bloodstream, which can result in elevated liver enzymes on blood tests. The specific elevated liver enzymes most commonly found are: Alanine transaminase (ALT) Aspartate transaminase (AST)
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What medications can cause liver enzymes to be elevated?
What medications can cause increased liver enzyme tests (AST and ALT) levels?
- aspirin,
- acetaminophen (Tylenol and others),
- ibuprofen (Advil, Motrin),
- naproxen (Naprosyn, Naprelan, Anaprox, Aleve),
- diclofenac (Voltaren, Cataflam, Voltaren-XR), and.
- phenylbutazone (Butazolidine)
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What can cause your liver enzymes to be slightly elevated?
Other causes of elevated liver enzymes may include: Alcoholic hepatitis (severe liver inflammation caused by excessive alcohol consumption) Autoimmune hepatitis (liver inflammation caused by an autoimmune disorder) Celiac disease (small intestine damage caused by gluten)
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Can gallbladder problems cause elevated liver enzymes?
About 40% of pancreatitis cases are associated with gallstones. Blood tests showing high levels of pancreatic enzymes (amylase and lipase) usually indicate a diagnosis of pancreatitis. Elevated levels of the liver enzyme alanine aminotransferase (ALT) are helpful in identifying gallstone pancreatitis.
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What not to eat with elevated liver enzymes?
Here are a few foods to include in your healthy liver diet:
- Coffee to lower abnormal liver enzymes.
- Greens to prevent fat buildup.
- Tofu to reduce fat buildup.
- Fish for inflammation and fat levels.
- Oatmeal for energy.
- Walnuts to improve the liver.
- Avocado to help protect the liver.
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Is bananas good for your liver?
Fish like cod, salmon, and sardines are good sources. It's also in veggies including broccoli, peas, and sweet potatoes, and fruits such as bananas, kiwi, and apricots. Dairy foods, like milk and yogurt, are also high in potassium. Early studies suggest betaine helps protect your liver from fatty deposits.
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What foods are good for liver repair?
Incorporate some of them into your diet to naturally cleanse and clean this vital organ!
- Grapefruit. Vitamin C could play a role in keeping your liver healthy; research has indicated it can help people with liver cirrhosis.
- Avocados.
- Beets.
- Turmeric.
- Garlic.
- Arugula.
- Cabbage.
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What vitamins are good for liver repair?
Antioxidant vitamins such as C, E, and beta-carotene; minerals such as zinc and selenium; B-vitamins that aid alcohol metabolism; and herbs said to "cleanse" the liver such as milk thistle, dandelion root, and schizandra, might help protect liver cells while ridding our body of poisons.
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Can a damaged liver heal itself?
The liver's healing process. This is known as liver cirrhosis. If excessive alcohol use and scarring continues over time, eventually the liver can become too scarred to function properly. Some alcohol-related liver damage can be reversed if you stop drinking alcohol early enough in the disease process.
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What foods cleanse your liver?
14 Foods That Cleanse the Liver
- Garlic. Just a small amount of this pungent white bulb has the ability to activate liver enzymes that help your body flush out toxins.
- Grapefruit.
- Beets and Carrots.
- Green Tea.
- Leafy Green Vegetables.
- Avocados.
- Apples.
- Olive Oil.
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How many years does it take to damage your liver?
About 10 to 20 percent of heavy drinkers usually develop cirrhosis after 10 or more years. Generally, drinking 80 grams of ethanol daily for 10 to 20 years is required to develop cirrhosis which corresponds to approximately one liter of wine, eight standard sized beers, or one half pint of hard liquor each day.
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How do I clean my liver?
Follow these six steps to help boost your health and vitality:
- Remove toxic foods from your diet.
- Drink raw vegetable juice.
- Load up on potassium-rich foods.
- Do a coffee enema.
- Take milk thistle, dandelion and turmeric supplements.
- Eat liver or take beef liver tablets.
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How much do you have to drink to damage your liver?
Consuming 3 ounces a day involves drinking 6 cans of beer, 5 glasses of wine, or 6 shots of liquor. About half the men who drink more than 8 ounces of alcohol a day for 20 years develop cirrhosis. Generally, the more and the longer people drink, the greater their risk of alcoholic liver disease.