What does it mean if Coombs test is negative?

Indirect Coombs test. A negative test result means that your blood is compatible with the blood you are to receive by transfusion. A negative indirect Coombs test for Rh factor (Rh antibody titer) in a pregnant woman means that she has not developed antibodies against the Rh-positive blood of her baby.
A.

What does Coombs positive mean in newborn?

It means that a blood test, called a Coombs test, or Direct Antibody Test (DAT), was done on your baby and was positive. This test is frequently performed on newborn babies. Usually the blood is taken from the baby's cord while it is attached to the placenta following delivery. Sometimes it is taken from the baby.
  • What is a positive DAT?

    The direct antiglobulin test (DAT) is used to determine whether red blood cells (RBCs) have been coated in vivo with immunoglobulin, complement, or both. The direct antiglobulin test is sometimes colloquially referred to as the Coombs test, because it is based on a test developed by Coombs, Mourant, and Race.
  • What does it mean Coombs test is negative?

    A negative Coombs test indicates that the fetus is not presently in danger from problems relating to Rh incompatibility. An abnormal (positive) result means that the mother has developed antibodies to the fetal red blood cells and is sensitized.
  • What is meant by incompatible blood types?

    A mother and child may also have an ABO blood type incompatibility, which can also cause hemolytic disease of the newborn. However, this incompatibility usually has less serious consequences. It occurs when the mother is type O and the baby is A, B, or AB.
B.

What does positive antibodies mean?

Your test is positive if it finds antinuclear antibodies in your blood. A negative result means it found no ANAs. A positive result may mean that you have an autoimmune disease such as lupus. About 95% of people with lupus will test positive for antinuclear antibodies.
  • What does positive antibodies mean?

    Your test is positive if it finds antinuclear antibodies in your blood. A negative result means it found no ANAs. A positive result may mean that you have an autoimmune disease such as lupus. About 95% of people with lupus will test positive for antinuclear antibodies.
  • What does it mean to have a positive antibody screen?

    An RBC antibody screen is used to screen an individual's blood for antibodies directed against red blood cell (RBC) antigens other than the A and B antigens. It is performed as part of a "type and screen" whenever a blood transfusion is anticipated or as part of prenatal testing of pregnant women.
  • What are the 11 criteria for lupus?

    11 SLE criteria, from the Lupus Research Institute:
    • Malar rash: butterfly-shaped rash across cheeks and nose.
    • Discoid (skin) rash: raised red patches.
    • Photosensitivity: skin rash as result of unusual reaction to sunlight.
    • Mouth or nose ulcers: usually painless.
C.

What does it mean to have a positive antibody screen?

An RBC antibody screen is used to screen an individual's blood for antibodies directed against red blood cell (RBC) antigens other than the A and B antigens. It is performed as part of a "type and screen" whenever a blood transfusion is anticipated or as part of prenatal testing of pregnant women.
  • What is a positive blood type?

    A person with an A positive blood type has antigen A on red cells. Having the presence of A antigen, A positive blood type can accept A+ and A-, along with A and B antigen free blood types O+ and O-. Transfusions with any other blood group can trigger an immune response.
  • What does it mean if you have red blood cell antibodies?

    Red blood cell (RBC) antibody identification is used as a follow-up test to a positive RBC antibody screen or a positive direct antiglobulin test (DAT). A DAT or RBC antibody screen is performed: On a pregnant woman during each pregnancy to determine whether the mother has developed any red blood cell (RBC) antibodies.
  • What does it mean to type and cross?

    The goal of blood typing and crossmatching is to find a compatible blood type for transfusion. If your crossmatch finds no antibodies, you have a very low possibility that your blood type will be incompatible with the donor type. If your crossmatch comes back positive, it means it's likely that antibodies were found.

Updated: 1st October 2018

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