2nd October 2019


How does norepinephrine affect mood?

Depression is associated with low levels of serotonin and norepinephrine. These are neurotransmitters (chemical messengers) known to affect mood. Serotonin is sometimes called a “feel-good” chemical because it's associated with positive feelings of wellbeing. Norepinephrine is related to alertness and energy.

So, what are the symptoms of low norepinephrine?

That is why sudden bursts of norepinephrine are often linked to anxiety, elevated blood pressure, and hyperactivity. Low levels, on the other hand, can cause lethargy, inattention, and lack of focus and concentration.

What does the drug norepinephrine do?

The Food and Drug Administration (FDA) has approved these SNRIs to treat depression:
  • Desvenlafaxine (Pristiq, Khedezla)
  • Duloxetine (Cymbalta) ? also approved to treat anxiety and certain types of chronic pain.
  • Levomilnacipran (Fetzima)
  • Venlafaxine (Effexor XR) ? also approved to treat anxiety and panic disorder.

What is the use of norepinephrine?

Norepinephrine is similar to adrenaline. It works by constricting (narrowing) the blood vessels and increasing blood pressure and blood glucose (sugar) levels. Norepinephrine is used to treat life-threatening low blood pressure (hypotension) that can occur with certain medical conditions or surgical procedures.
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