25th November 2019

cvpharmacology
12

How do loop diuretics cause hypokalemia?

Because loop and thiazide diuretics increase sodium delivery to the distal segment of the distal tubule, this increases potassium loss (potentially causing hypokalemia) because the increase in distal tubular sodium concentration stimulates the aldosterone-sensitive sodium pump to increase sodium reabsorption in

Likewise, which diuretics are potassium sparing?

Examples of potassium-sparing diuretics include:
  • Amiloride.
  • Eplerenone (Inspra)
  • Spironolactone (Aldactone)
  • Triamterene (Dyrenium)

Is chlorothiazide a potassium sparing?

Groups commonly used are thiazide diuretics and thiazide-like diuretics (chlorothiazide, chlorthalidone, hydrochlorothiazide, indapamide, and metolazone), loop diuretics (bumetanide, furosemide, and torsemide), potassium-sparing diuretics (amiloride, spironolactone, and triamterene), and osmotic diuretics (mannitol).
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