If you're referring to a normal PC, no, you can't run it without separate RAM sticks attached, but that's only because the BIOS is designed not to attempt to boot with no RAM installed (which is, in turn, because all modern PC operating systems require RAM to run, especially since x86 machines typically don't allow you
Accordingly, can Ram get damaged?
Electrostatic discharge can damage your computer. If you have overclocked any part of your computer incorrectly, it may cause damage in the form of excess heat. Your memory module may have some fault that passed through quality control and worsened over time. This is the most likely cause behind a damaged RAM.
What does bad RAM mean?
Random Access Memory (RAM) wears out over time. If your PC frequently freezes, reboots, or brings up a BSOD (Blue Screen Of Death), bad RAM just might be the problem. Corrupt files can be another sign of bad RAM, especially when the corruption is found in files that you've used recently.
Can RAM cause the blue screen of death?
A bad memory module (RAM) can cause unpredictable behavior in a Windows system, including the dreaded blue screen of death. If you suspect that your RAM may be faulty, you can run a memory test to confirm that you have a bad memory module.