Can a mutation which occurs in a somatic cell be inherited?
Somatic mutations can occur in any of the cells of the body except the germ cells (sperm and egg) and therefore are not passed on to children. These alterations can (but do not always) cause cancer or other diseases.
Most mutations to the DNA are heritable, but not all are inherited. Mutations occur in the DNA, DNA is then replicated and transmitted to offspring (cells or organisms).
- Most random genetic changes caused by evolution are neutral, and some are harmful, but a few turn out to be positive improvements. These beneficial mutations are the raw material that may, in time, be taken up by natural selection and spread through the population.
- Mutations are random. Mutations can be beneficial, neutral, or harmful for the organism, but mutations do not "try" to supply what the organism "needs." Factors in the environment may influence the rate of mutation but are not generally thought to influence the direction of mutation.
- But the mutations we hear about most often are the ones that cause disease. Some well-known inherited genetic disorders include cystic fibrosis, sickle cell anemia, Tay-Sachs disease, phenylketonuria and color-blindness, among many others. All of these disorders are caused by the mutation of a single gene.
The only mutations that matter to large-scale evolution are those that can be passed on to offspring. These occur in reproductive cells like eggs and sperm and are called germ line mutations. A single germ line mutation can have a range of effects: No change occurs in phenotype.
- One side of the DNA is copied how? How can a mutation in the DNA cause a change in an organism's protein? If the codon is in the amino acids change, then the protein will be different. Do all mutations in the DNA coding got mRNA cause a change in an organism?
- Beneficial - The mutation changes the sequence of amino acids in a way that the phenotype expressed will give the organism an advantageous characteristics. For example, some mutations mean that bacteria are resilient to antibiotics, this means they will survive.
- Genetic changes that are described as de novo (new) mutations can be either hereditary or somatic. In some cases, the mutation occurs in a person's egg or sperm cell but is not present in any of the person's other cells.
Mutations can occur in either cell type. If a gene is altered in a germ cell, the mutation is termed a germinal mutation. Because germ cells give rise to gametes, some gamete s will carry the mutation and it will be passed on to the next generation when the individual successfully mates.
- It starts in one cell, and then is passed on to any new cells that are created from that cell. This kind of mutation is not present in egg or sperm cells, so it is not passed on to the next generation. Acquired mutations are much more common than inherited mutations. Most cancers are caused by acquired mutations.
- What would happen if cells with mutated DNA replicated? If cells with mutated DNA replicated, it would spread to other cells during mitosis. Once this occurs more cells with the mutation will reproduce and ultimately the result will almost always be cancer due to the rapid division of cells.
- The only mutations that matter to large-scale evolution are those that can be passed on to offspring. These occur in reproductive cells like eggs and sperm and are called germ line mutations. A single germ line mutation can have a range of effects: No change occurs in phenotype.
Updated: 26th October 2019